Clinical Studies
Traumatic Brain Injury – Neurosurgical pathologies

Clinical Outcomes of MLC601 (NeuroAiD™ ) in Traumatic Brain Injury: A Pilot Study.

Traumatic Brain Injury – Neurosurgical pathologies

MLC901 (NeuroAiD II™) for cognition after traumatic brain injury: a pilot randomized clinical trial.

Ischemic Stroke

NurAiD-II in stroke recovery: scientific reasoning and real-world evidence.

Publication : De Le Cruz Cosme C. International Journal of Clinical Neurosciences and Mental Health 2017.

Cognitive Disorders and Dementia

MLC601 in vascular dementia: an efficacy and safety pilot study.

Publication : Pakdaman H, et al. Neuropsychiatric Disease and Treatment 2017. DOI: 10.2147/NDT.S145047

Participation Size : 81

Efficacy and Safety of MLC601 in the Treatment of Mild Cognitive Impairment: A Pilot, Randomized, Double-Blind, Placebo-Controlled Study.

Ischemic Stroke

CHInese Medicine NeuroAiD Efficacy on Stroke Recovery – Extension Study (CHIMES-E): A Multicenter Study of Long-Term Efficacy.

Publication : Venketasubramanian N, et al. Cerebrovascular Diseases 2015. DOI: 10.1159/000382082

Participation Size : 880

Sponsor : CHIMES Society



Cognitive Disorders and Dementia

Effectiveness and Safety of MLC601 in the Treatment of Mild to Moderate Alzheimer’s Disease: A Multicenter, Randomized Controlled Trial.

Ischemic Stroke

A Randomized Trial to Assess the Long-Term Safety of NeuroAiD among Caucasian Patients with Acute Ischemic Stroke.

Ischemic Stroke

Chinese Medicine Neuroaid Efficacy on Stroke Recovery: A Double-Blind, Placebo-Controlled, Randomized Study.

Publication : Chen C, et al. Stroke 2013. DOI: 10.1161/STROKEAHA.113.002055

Participation Size : 1099

Sponsor : CHIMES Society



Cognitive Disorders and Dementia

Efficacy and Tolerability of MLC601 in Patients with Mild to Moderate Alzheimer Disease Who Were Unable to Tolerate or Failed to Benefit from Treatment with Rivastigmine.

Publication : Harandi AA, et al. Brit Med Med Res 2013.

Participation Size : 124

Sponsor : Shahid Beheshti University of Medical Sciences

Ischemic Stroke

The Use of NeuroAiD (MLC601) in Post ischemic Stroke Patients.

Publication : Navarro JC, et al. Rehabil Res Pract 2012. DOI: 10.1155/2012/506387

Participation Size : 30

Safety and efficacy of MLC601 in Iranian patients after stroke: a double-blind, placebo-controlled clinical trial.

Publication : Harandi AA, et al. Stroke Res Treat 2011. DOI: 10.4061/2011/721613

Participation Size : 150

Sponsor : Shahid Beheshti University

Ischemic Stroke

The effect of NeuroAiD (MLC601) on cerebral blood flow velocity in subjects’ post brain infarct in the middle cerebral artery territory.

Publication : Shahripour RB, et al. Eur Intern Med 2011. DOI: 10.1016/j.ejim.2011.01.002

Participation Size : 80

NeuroAiD (MLC601) versus piracetam in the recovery of post-infarct homonymous hemianopsia.

Publication : Ghandehari K, et al. Neural Regen Res 2011. DOI: 10.3969/j.issn.1673-5374.2011.06.003

Participation Size : 40

Sponsor : Moleac Pte. Ltd.

Traumatic Brain Injury – Neurosurgical pathologies

Case Report on the Use of MLC601 (NeuroAiD) in Neurosurgical Pathologies.

Publication : Yeo TT, et al. Poster WSC Seoul 2010.

Participation Size : 3

Ischemic Stroke

A Double-Blind, Placebo-Controlled, Randomized Phase II Pilot Study to Investigate the Potential Efficacy of the Traditional Chinese Medicine NeuroAiD (MLC601) in Enhancing Recovery after Stroke (TIERS).

Publication : Kong KH, et al. Cerebrovasc Dis 2009.DOI: 10.1159/000247001

Participation Size : 40

Sponsor : Moleac Pte Ltd.

NeuroAiD (Danqi Piantang Jiaonang), a Traditional Chinese Medicine, in Poststroke Recovery.

Publication : Chen C, et al. Stroke 2009. DOI: 10.1161/STROKEAHA.108.531616

Participation Size : 605

Sponsor : Tianjin University of Traditional Chinese Medicine

Ischemic Stroke

NeuroAiD Danqi Piantang Jiaonang Does Not Modify Hemostasis, Hematology, and Biochemistry in Normal Subjects and Stroke Patients.

Publication : Gan R, et al. Cerebrovasc Dis 2008. DOI: 10.1159/000126919

Participation Size : 64

NeuroAiD in Stroke Recovery.

Publication : Siow C, Eur Neurol 2008. DOI: 10.1159/000155220

Participation Size : 10

Spinal Cord Injury

Assessing Tolerability and Use of Combined Rehabilitation and NeuroAiD (SATURN Study): Protocol of An Exploratory Study In Assessing the Safety and Efficacy of NeuroAiD Amongst People Who Sustain Severe Spinal Cord Injury.

Publication : Kumar JC et al. JMIR Res Protoc 2016. DOI: 10.2196/resprot.6275

Participation Size : 26

Sponsor : Moleac Pte. Ltd.

The NeuroAiD Safe Treatment (NeST) Registry: a protocol.

Publication : Venketasubramanian N, et al. BJM Open 2015. DOI:10.1136/bmjopen-2015-009866

Participation Size : 460

Sponsor : CHIMES Society

The NeuroAiD II (MLC901) in Vascular Cognitive Impairment Study (NEURITES).

Publication : Chen C, et al. Cerebrovasc Dis 2013.DOI: 10.1159/000346234

Participation Size : 103

Sponsor : National University Hospital, Singapore

The Alzheimer’s disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer’s disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial.