The Gut-Brain Connection: Understanding Gastrointestinal Dysfunction After TBI

๐ฐ๐ง ๐ฌ TRAUMATIC BRAIN INJURY STUDY HIGHLIGHTS – Gastrointestinal disorders in traumatic brain injury: pathophysiology, risk factors, and interventions by Fu AY., et al.
Gastrointestinal (GI) dysfunction is increasingly recognized as a common complication after Traumatic brain injury (TBI). This review aims to improve understanding of the causes, risk factors, and management of GI disorders after TBI to support better clinical care.
๐ฃ๐ฎ๐๐ต๐ผ๐ฝ๐ต๐๐๐ถ๐ผ๐น๐ผ๐ด๐ ๐ฎ๐ป๐ฑ ๐ฐ๐น๐ถ๐ป๐ถ๐ฐ๐ฎ๐น ๐ฒ๐ณ๐ณ๐ฒ๐ฐ๐๐
GI dysfunction after TBI may occur due to autonomic nervous system dysfunction, increased intracranial pressure, and systemic inflammation. These changes can impair intestinal movement and nutrient absorption, leading to feeding intolerance and malnutrition. Possible indicators include high gastric residual volume, weight loss, low body mass index, and low albumin levels.
๐ง๐ฟ๐ฒ๐ฎ๐๐บ๐ฒ๐ป๐ ๐ฎ๐ป๐ฑ ๐ฐ๐ฎ๐ฟ๐ฒ
Management strategies include nutritional screening, prokinetic medications that stimulate gut motility, and small bowel or transpyloric feeding. Early recognition and appropriate nutritional support may help improve recovery and overall patient outcomes.
๐ Access the full article at: Fu, A. Y., Elguindy, M. M., Manley, G. T., & Yue, J. K. (2025). Gastrointestinal disorders in traumatic brain injury: pathophysiology, risk factors, and interventions. Journal of neurosurgical sciences, 69(6), 469โ480. https://www.minervamedica.it/en/journals/neurosurgical-sciences/article.php?cod=R38Y2025N06A0469. This is an open-access article under a CC BY-NC 4.0 license.